Single-Use Sterile Connectors for Cell Therapy

A Matter of Integrity

The cutting-edge work of cell and gene therapy research and development does not match the integrity of the process. Now is the time to match the innovation and promise of advanced therapies with the manufacturing process of getting patients these therapies they desperately need.

Risk Mitigation with Closed System Processing

Fast Connections and Easy-to-Use

MicroCNX^® sterile connectors provide quick connections, even in non-sterile environments - a critical capability for your biopharmaceutical manufacturing.

Fast and easy-to use - 4x faster than tube welding
80% cost reduction in labor
Less downtime and increased reliability when using sterile connectors

Request a Sample

Additional Resources

View Resources

Innovations in Cell and Gene Therapy Manufacturing

Learn how to improve operations, maintain flexibility and overcome challenges.

Flow with Confidence: Innovations that foster flexibility and scale in closed-system manufacturing

Explore how sterile connectors enable fast, easy, and sterile connections while minimizing hold-up volume, ensuring greater precision and cost efficiency.

The Case for Modernizing Small-volume Aseptic Processing

Maintaining sterility for therapeutics that biopharmaceutical and cell and gene manufacturers produce is critical – particularly when unique, personalized samples are processed for precision medicine.

Regulatory Compliance

Manufacturing failure rates can be as high as 10% compared to the biologics space. Sterile connectors are essential to closing your process and the key to reducing failure rates.

7 out of 10 FDA rejections are caused by CMC failures – these issues are preventable
On average, the FDA requested protocol amendments took an average of ~5 months to resolve

Request a Sample

Additional Resources

View Resources

Innovations in Cell and Gene Therapy Manufacturing

Learn how to improve operations, maintain flexibility and overcome challenges.

Automation, robotics, and reducing risk in cell therapy manufacturing

In Episode 2 hosted by Nik Ekman, Application Development Manager for CPC Biopharma, he invites Fred Parietti, Co-founder of Multiply Labs to discuss automation and robotics in cell therapy manufacturing.

Mitigating Risk in Bioprocess Manufacturing Amid New Single-Use Regulations

Mitigate risk using modular systems and the new regulations around single-use technology.

Scaling for commercialization

Sterile, single-use connectors allow for scaling in three critical ways: sterility assurance, process efficiency and flexibility, and reducing cross-contamination risk

Sterile connectors drastically reduce the risk of microbial contamination that could compromise the final batch as media volumes increase
Quick, secure and reproducible connections minimize manual handling
SUTs enable rapid production adaptation to meet varying batch sizes and demands

Request a Sample

Additional Resources

View Resources

Innovations in Cell and Gene Therapy Manufacturing

Learn how to improve operations, maintain flexibility and overcome challenges.

Scale for the Future

As cell and gene therapy companies work to deliver life-changing results to as many people as possible, questions about scale loom large. Our distinguished speaker, Eoin Dolan, will review the topics ahead.

Automation, robotics, and reducing risk in cell therapy manufacturing

In Episode 2 hosted by Nik Ekman, Application Development Manager for CPC Biopharma, he invites Fred Parietti, Co-founder of Multiply Labs to discuss automation and robotics in cell therapy manufacturing.

Error Showing Content - please login as admin for details.

What are MicroCNX^® Series Connectors?

The small-format MicroCNX series connectors increase process design flexibility by integrating with different tubing sizes and materials. Their robust design, including innovative valves and genderless format, provides uncompromising reliability. Aseptic MicroCNX connectors help manufacturers be more efficient, reduce time, lower total costs and mitigate risk.

The Connector Solution for Cell and Gene Therapy.

MicroCNX family

MicroCNX Nano

Specifically designed for the challenging conditions of biological media transfer in CGT applications. It can withstand ultra low temperatures down to -190°C (cryogenic freezing applications)and is the lowest profile connector in the industry; ensuring a fit into any freezing cassette used in CGT processing. Like the original MicroCNX standard connector, the MicroCNX Nano provides a simple, efficient method of connecting tubing for small-format biomanufacturing assemblies. The MicroCNX Nano comes in 1/8", 3/32", and 1/16" hose barb terminations for connection to a variety of tubing types including silicone, TPE and PVC.

MicroCNX Nano specification data

MicroCNX ULT

The connector solution for cryogenic freezing applications and connections using PVC tubing. The MicroCNX ULT can be frozen down to vaporized liquid nitrogen temperatures (-190° C) and has increased compatibility with harsh chemicals. The MicroCNX ULT connects to 1/16”, 3/32” and 1/8” tubing sizes and can be gamma irradiated up to 50kGy and autoclaved one cycle up to 250° F for 30 minutes.

MicroCNX Ult product table

MicroCNX Standard

The first aseptic, single-use connector on the market for small-format tubing, and the most efficient alternative to tube welding. The MicroCNX standard connects to 1/16”, 3/32” and 1/8” tubing and eases specification with one part number for both halves. The easy-to-use three step connection process reduces risk of operator error.

MicroCNX product table

MicroCNX Luer

The first aseptic, single-use connector on the market. The MicroCNX Luer is a sterile connection solution that enables a technician to make connections inside of the biosafety cabinet. The MicroCNX Luer termination comes in a 1/8” flow path and has female and male terminations. Also, lowers risk of operator error and related performance, reliability and safety concerns. The easy-to-use three step connection process reduces risk of operator error.for small-format tubing, and the most efficient alternative to tube welding. The MicroCNX standard connects to 1/16”, 3/32” and 1/8” tubing and eases specification with one part number for both halves. The easy-to-use three step connection process reduces risk of operator error.

MicroCNX Luer product table

Knowledge Center

Resources

Support

About CPC

Company

Capabilities

Micro is Macro

Adopting one micro solution - aseptic connectors - can
have macro impacts on cell processing.

A Matter of Integrity